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Traian
Chirila
- Current research activities
The three major projects in my department that are relevant to
tissue engineering include:
I. Non-biodegradable scaffolds for artificial cornea
II. Novel one-step process for the production of biodegradable
porous scaffolds
III. Molecular mechanism of calcification of polymer implants
- Keywords
polymers, biomaterials, polymer scaffolds for TE, biocompatibility,
ocular implants, polymer matrix for sustained release of drugs.
- End-user applications
- Improved ocular implants
- Simpler ways to produce porous scaffolds
- Key publications
| I. |
T.V.Chirila et al. Poly(2-hydroxyethyl methacrylate)
sponges as implant materials: in vivo and in vitro evaluation
of cellular invasion. Biomaterials, 14(1): 26-38,
1993 |
| II. |
T.V.Chirila et al. Interpenetrating polymer network (IPN)
as a permanent between the elements of a new type of artificial
cornea. J. Biomed. Mater. Res., 28(6): 745-753, 1994 |
| III. |
T.V.Chirila. Modern artificial corneas: the use of porous
polymers. Trends Polym. Sci., 2(9): 296-300, 1994 |
| IV. |
T.V.Chirila et al. Artificial cornea. Prog. Polym.
Sci.,_23(3): 447-473, 1998 |
| V. |
G.W.Plant, T.V.Chirila, A.R.Harvey. Implantation of collagen
IV/poly(2-hydroxyethyl methacrylate) hydrogels containing
Schwann cells into the lesioned rat optic tract. Cell
Transplantation, 7(4): 381-391, 1998 |
- Outreach activities
Member in organizing committees of 98 Workshop on Tissue Engineering,
Tianjin, China, 1998; The First international Conference on Medical
Implants, Bethesda, USA, 2003.
Lectures presented at:
The 2nd Cottesloe Beach Symposium: Stem Cells and Tissue Engineering,
Perth, Australia, 2002 (“Non-biodegradable polymer scaffolds
for tissue engineering”).
Bioscience Frontiers for the Real World 2002 Conference: Frontiers
in Tissue Engineering,
Brisbane, Australia, 2002 (“Biointegration of non-biodegradable
matrix: the artificial cornea story”).
- Key organisation membership
Australian tissue engineering interest groups (STEAM)
Australian Society for Biomaterials
- Early career researcher?
No.
- Young investigator?
No.
- Skills and expertise
- polymer synthesis
- evaluation of biomaterials
- Specialist equipment and infrastructure
- Fully equipped laboratories for organic and polymer synthesis
- Rheometer
- Fully equipped tissue culture laboratory
- Microscopy and histopathology facilities
© 2004
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