Rolfe Howlett
  1. Current research activities

    2. a. Comparative Orthopaedic pathologist working in tissue engineering for many years
    b. Expert in the interpretation the tissue medical device interface
    c. published extensively in healing and regenerative tissue responses(soft and hard) not only in animals but man.

  2. Keywords

    3. Bone, biomaterials, tissue engineering, skeletal pathology, medical prostheses.

  3. End-user applications

    • Orthopaedic biomaterials and joint prostheses
    • Vascular stents and other cardiac medical devices
    • Replacement of large bone defects scaffolds + osteogenic cells
    • Articular cartilage healing
  4. Key publications

    5. I. Howlett et al 1989 “the effect of Silicon Nitride Ceramic on Rabbit skeletal cells and Tissue Clin.Orthop and rela research.244:293-304
    II. Howlett et al(1994) the effect of magnesium ion implantation into alumina upon the adhesion of human bone derived cells Journal of material science: materials in medicine 5:715-722.
    III. Howlett et al (2000) Effects of Biomaterial chemistries on the osteoblastic molecular phenotype and osteogensis in vitro and in vivo in “ Bone engineering” ed JE Davies emsquarted incorporated ,Toronto , Canada pp240-256.
    IV. Lickorish, D. Ramshaw, werkeister,Glauttauer & Howlett(2004)_Collagen hydroxyapatite construct prepared by Biomimetic process.J Biomedical Materials Research 68A :19-27
    V. Pabbruwe, M. B., O.C. Standard, C. C. Sorrell, C.R.Howlett, (2004).Bone formation within Alumina tubes: Effect of Calcium, Manganese and Chromium Dopants. Biomaterials 25:4901-4910
    VI. Revell , P. A. Damien, E., Zhang, X. S., Evans, P., Howlett, C. R. “The Effect of Magnesium Ions on Bone Bonding to Hydroxyapatite Coating on Titanium Alloy Implants” J. Mater. Sci.: Mater. Medicine (In Press)

  5. Outreach activities

    6. None as Yet.

  6. Key organisation membership

    7. Australian tissue engineering interest groups

  7. Early career researcher?

    8. No.

  8. Young investigator?

    9. No.

  9. Skills and expertise

    •  tissue culture
    • orthopaedic pathologist
    • veterinary pathologist · _
    • electron microscopist(TEM & SEM)
  10. Specialist equipment and infrastructure

    • Usual tissue culture materials and hoods
    • Diamond saws and microgrinder for preparation of microscopic
    • Slides containing skeletal tissue and ceramics ,metals and polymers 

© 2004

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