Raju Adhikari
  1. Current research activities

    2. Our current research is focused on the development of biodegradable polymers for tissue engineering in orthopaedic, soft tissue and cartilage fields. We have developed a family of biodegradable polymers that can deliver cells and growth factors for repair of bone and cartilage defects. The polymers are designed to provide easy cell delivery techniques and curing strategies such that they minimize the requirement for invasive surgery. This polymer technology has the potential for use in other fields such as drug delivery, soft tissue and organ repair, adhesive and wound repair.

  2. Keywords

    3. Biodegradable polymer, Scaffolds, Injectable, Porous, Biocompatible , Tissue engineering.

  3. End-user applications

    • Cartilage repair
    • Bone repair
    • Drug delivery
    • Adhesive
    • Wound healing

  4. Key publications

    5. I. Gunatillake PA. And Adhikari R.( 2003) Biodegradable synthetic polymer for Tissue engineering, European Cells and Materials Vol 5, 1-16.
    II. Adhikari R., Gunatillake PA., Bown M. (2003) Effect of Poly(dimethylsiloxane) on morphology and properties of Polyurethanes and Polyurethaneureas., Journal of Applied Polymer Science, 90, 6, 1565-1573
    III. Gunatillake PA., Martin D., Mejis GF., McCarthy SJ and Adhikari R., (2003)Polyurethanes in biomedical application., Journal of Australian Chemistry, 56, 545-557.
    IV. Raju Adhikari, Craig L. Francis, Gregory W. Simpson and Qi. Yang. Selective Protection Strategies in the Synthesis of TRIS-Fatty Ester Derivatives, Australian Journal of Chemistry, (2002), 55, 629-634.
    V. Adhikari R., Gunatillake PA., Mejis GF., McCarthy SJ. Low Modulus Siloxane-Based Polyurethanes: Part II-Effect of the chain extender on Properties and Morphology., Journal of Applied Polymer Science, Journal of Applied Polymer Science, 87, 7, 14, pp. 1092 – 1100

  5. Outreach activities

    6. None as Yet.

  6. Key organisation membership

    7. None as Yet.

  7. Early career researcher?

    8. No.

  8. Young investigator?

    9. No.

  9. Skills and expertise

    • Design & synthesis of Biostable polyurethanes for chronic implant devices
    • Biodegradable Polymers for Tissue Engineering Applications in Scaffold fabrication, Injectable Polymer Systems
    • Interactions of synthetic polymers with biological environment, degradation, cell compatibility
    • Development of Tissue engineered products/therapies for; Cartilage repair and bone healing
    • Technology Transfer, scale-up manufacture
    • In-vitro and In vivo evaluation of materials
    • Structure property relationship of synthetic polymers (polyurethanes

  10. Specialist equipment and infrastructure

    • Gel permeation chromatography
    • Nuclear Magnetic resonance spectrometer (400, 500 MHz)
    • Thermogravemetric analyser (TGA)
    • Mass spectrometer
    • XPS
    • SEM
    • Dynamic Mechanical Thermal Analysis (DMTA)
    • FTIR spectroscopy
    • Differential Scanning Calorimetry (DSC)
    • Microextruder
    • Injection moulding machine
    • Compression Moulding
    • Wiped-film evaporator (reagent purification)
    • Karl-Fisher moisture analyzer
  11. Contact Details 

    Dr Raju Adhikari
    Address: Applied Chemistry CSIRO Molecular Science
    Bayview Avenue Clayton South VIC 3169
    Country: Australia
    Phone: +61 3 9545 8048
    Fax: +61 3 9545 8050
    Email: Raju.Adhikari@csiro.au

© 2004

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