Hans Griesser
  1. Current research activities

    2. Surface modification of materials (polymers, metals, ceramics) for biomedical applications and devices, including surface treatments for the insertion of specific chemical groups into inert polymers, and the fabrication of bioactive coatings comprising covalently immobilized biomolecules, esp proteins, that can control interfacial responses to implanted materials and devices. In parallel, development of highly sensitive physico-chemical methods for the analysis of biomaterials and bioactive coatings. Patterning of surfaces for spatial control of bio-interfacial responses. Study of protein adsorption processes onto materials and device surfaces.

  2. Keywords

    3. Surface modification, bioactive coatings, protein immobilization, surface analysis, patterning, protein adsorption

  3. End-user applications

    • Bio-diagnostics
    • Tissue integration
    • Antibacterial coatings
    • Bone integration
    • Device sterilization

  4. Key publications

    5. I. P. Kingshott, H.A.W. StJohn and H.J. Griesser
    Identification of Proteins Adsorbed on Synthetic Materials by MALDI Mass Spectrometry. Analytical Biochemistry, 273, 156 (1999).
    II. P. Kingshott and H.J. Griesser
    Surfaces that Resist Bio-Adhesion – a Review.
    Current Opinion in Solid State and Materials Science, 4, 403 (1999).
    III. P. Vermette, H.J. Griesser, G. Laroche and R. Guidoin (Eds.),
    Biomedical Applications of Polyurethanes, Landes Publishing (2001).
    IV. H.J. Griesser, S.L. McArthur, M.S. Wagner, P. Kingshott, K.M. McLean and D.G. Castner XPS, ToF-SIMS and MALDI-MS for Characterizing Adsorbed Protein Films. In: Biopolymers at Interfaces, 2nd Edition, Ed. M. Malmsten, Marcel Dekker, 2003.
    V. H.J. Griesser, P. Kingshott, S.L. McArthur, K.M. McLean, G.R. Kinsel and R.B. Timmons Surface-MALDI Mass Spectrometry in Biomaterials Research (A Review). Biomaterials, accepted subject to minor revision.

  5. Outreach activities

    6. None as Yet.

  6. Key organisation membership

    7. Aust Soc Biomaterials

  7. Early career researcher?

    8. No.

  8. Young investigator?

    9. No.

  9. Skills and expertise

    • Surface modification
    • Biomolecule immobilization
    • Thin film coatings
    • Bio-diagnostics
    • Bioactive coatings
    • Spectroscopy
    • Patterning of surfaces
    • Surface analysis
    • Protein adsorption studies

  10. Specialist equipment and infrastructure

    • Surface characterization :
      • AFM
      • XPS
      • ToF-SIMS
      • Ellipsometer
      • MALDI-MS
      • Laser Raman and Infrared Spectroscopy
      • Contact angle goniometer
      • SEM
    • Surface modification :
      • Large and small units for surface modification of materials and devices

© 2004

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