1. Current research activities

   Development of ‘artificial’ blood vessels and other smooth muscle-rich organs using the peritoneal cavity as a bioreactor, plus the growth of supernumerary kidneys.

2. Keywords.

   blood vessels, myofibroblasts, transdifferentiation, adult stem cells, smooth muscle progenitors.

3. End-user applications


• Vascular grafts
• Kidneys for end-stage renal failure patients


4. Key publications

I.	Chue W-L, Campbell GR, Caplice N, Muhammed A, Berry CL, Thomas AC, and Campbell JH. The dog peritoneal and pleural cavities as bioreactors to grow autologous artificial blood vessels. J Vasc Surg (in press)
II.	Bayes-Genis A, Campbell JH, Carlson PJ, Holmes DR and Schwartz RS (2002) Macrophages, myofibroblasts and neointimal hyperplasia after coronary artery injury and repair. Atherosclerosis 163:89-98
III.	Campbell JH, Han C, Campbell GR (2001) Neointimal formation by circulating bone marrow cells. Ann NY Acad Sci. 947:18-25.
IV.	Campbell JH Efendy JL, Han C, Girjes AA, Campbell GR (2000) Haemopoietic origin of myofibroblasts formed in the peritoneal cavity in response to a foreign body. J Vasc Res 37:364-371.
V.	Campbell JH, Efendy JL, Campbell GR (1999) A novel vascular graft grown within the recipients own peritoneal cavity. Circ Res 85:1173-1178.



5. Outreach activities

   2020 Vision Lecture, University of Queensland

6. Key organisation membership
   
   None as Yet

7. Early career researcher?
   
   No.

8. Young investigator?
   
   No.

9. Skills and expertise


• cell biology
• cell culture
• biochemistry
• molecular biology
• animal surgery


10. Specialist equipment and infrastructure


• FACS
• microarray
  

© 2004

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